• There are some nerdy details about the differences between the Muscle and Neuron SpikerBox. The Muscle has three leads for differential amplification and wider filters, but yes, it can record from neurons in the cockroach leg. If budget is tight you can do that, if not we recommend buying both the Neuron And Muscle SpikerBox as the Neuron SpikerBox is optimized for insect experiments with the included electrodes and the muscle SpikerBox is optimized for human experiments.